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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TTC14 All Species: 15.45
Human Site: T453 Identified Species: 34
UniProt: Q96N46 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96N46 NP_597719.1 770 88319 T453 Q K T K K I E T S A E K L R K
Chimpanzee Pan troglodytes XP_001153924 699 78757 L406 K Q S A S W A L K C V K I G V
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535814 769 87731 T453 Q K T K K I E T S A E K L R K
Cat Felis silvestris
Mouse Mus musculus Q9CSP9 761 86774 K451 K I E T R A E K L R K L L K E
Rat Rattus norvegicus NP_001101136 768 87190 T452 Q K T K K I E T S A E K L R K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506381 699 78865 I406 S S V S S S D I P A S S S S S
Chicken Gallus gallus NP_001006552 788 90187 T453 E K E K Q V E T S A E K L R K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001014336 664 75110 Q371 N A K K Y L C Q T L V E R G G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VGU5 872 99852 T538 K E R R R S R T K S E T E D P
Honey Bee Apis mellifera XP_001121860 1247 141959 L460 K R K K E R K L R S K K R Q R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791418 1698 191424 M519 E E S S Q E Q M S A K Q L R E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 77.5 N.A. 90.5 N.A. 86.4 86.4 N.A. 64 62.6 N.A. 51.8 N.A. 23.5 22.3 N.A. 21
Protein Similarity: 100 77.5 N.A. 94.2 N.A. 91.6 92 N.A. 74.5 76.1 N.A. 66.4 N.A. 41.6 37.2 N.A. 31.4
P-Site Identity: 100 6.6 N.A. 100 N.A. 13.3 100 N.A. 6.6 73.3 N.A. 6.6 N.A. 13.3 13.3 N.A. 26.6
P-Site Similarity: 100 33.3 N.A. 100 N.A. 46.6 100 N.A. 13.3 93.3 N.A. 26.6 N.A. 46.6 66.6 N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 10 0 10 10 0 0 55 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 10 0 0 10 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 10 0 0 0 0 0 0 10 0 % D
% Glu: 19 19 19 0 10 10 46 0 0 0 46 10 10 0 19 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 19 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 0 28 0 10 0 0 0 0 10 0 0 % I
% Lys: 37 37 19 55 28 0 10 10 19 0 28 55 0 10 37 % K
% Leu: 0 0 0 0 0 10 0 19 10 10 0 10 55 0 0 % L
% Met: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 10 % P
% Gln: 28 10 0 0 19 0 10 10 0 0 0 10 0 10 0 % Q
% Arg: 0 10 10 10 19 10 10 0 10 10 0 0 19 46 10 % R
% Ser: 10 10 19 19 19 19 0 0 46 19 10 10 10 10 10 % S
% Thr: 0 0 28 10 0 0 0 46 10 0 0 10 0 0 0 % T
% Val: 0 0 10 0 0 10 0 0 0 0 19 0 0 0 10 % V
% Trp: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _